| 1 | Bradley Wright-Phillips
New York Red Bulls | New York Red Bulls | 36 | 25 |
| 2 | David Villa
New York City FC | New York City FC | 35 | 23 |
| 3 | Sebastian Giovinco
Toronto FC | Toronto FC | 34 | 21 |
| - | Ignacio Piatti
CF Montréal | CF Montréal | 37 | 21 |
| 5 | Ola Kamara
Columbus Crew SC | Columbus Crew SC | 25 | 16 |
| - | Fanendo Adi
Portland Timbers | Portland Timbers | 33 | 16 |
| - | Dom Dwyer
Sporting Kansas City | Sporting Kansas City | 34 | 16 |
| 8 | Jozy Altidore
Toronto FC | Toronto FC | 29 | 15 |
| - | Giovani Dos Santos
LA Galaxy | LA Galaxy | 31 | 15 |
| 10 | Cyle Larin
Orlando City SC | Orlando City SC | 32 | 14 |
| - | Diego Valeri
Portland Timbers | Portland Timbers | 30 | 14 |
| - | Jordan Morris
Seattle Sounders FC | Seattle Sounders FC | 40 | 14 |
| 13 | Frank Lampard
New York City FC | New York City FC | 21 | 12 |
| - | Chris Pontius
Philadelphia Union | Philadelphia Union | 34 | 12 |
| - | Chris Wondolowski
San Jose Earthquakes | San Jose Earthquakes | 30 | 12 |
| 16 | Kevin Molino
Orlando City SC | Orlando City SC | 30 | 11 |
| 17 | Robbie Keane
LA Galaxy | LA Galaxy | 20 | 10 |
| - | Didier Drogba
CF Montréal | CF Montréal | 25 | 10 |
| - | Lamar Neagle
D.C. United | D.C. United | 32 | 10 |
| - | Shkëlzen Gashi
Colorado Rapids | Colorado Rapids | 30 | 10 |
| - | Joao Plata
Real Salt Lake | Real Salt Lake | 31 | 10 |
| - | Maximiliano Urruti
FC Dallas | FC Dallas | 32 | 10 |
| 23 | Roland Alberg
Philadelphia Union | Philadelphia Union | 29 | 9 |
| - | David Accam
Chicago Fire FC | Chicago Fire FC | 24 | 9 |
| - | Kaká
Orlando City SC | Orlando City SC | 24 | 9 |
| - | Pedro Morales
Vancouver Whitecaps FC | Vancouver Whitecaps FC | 27 | 9 |
| - | Yura Movsisyan
Real Salt Lake | Real Salt Lake | 30 | 9 |
| - | Michael Barrios
FC Dallas | FC Dallas | 34 | 9 |
| 29 | Patrick Mullins
D.C. United | D.C. United | 13 | 8 |
| - | Clint Dempsey
Seattle Sounders FC | Seattle Sounders FC | 17 | 8 |
| - | Nicolás Lodeiro
Seattle Sounders FC | Seattle Sounders FC | 19 | 8 |
| - | Dominic Oduro
CF Montréal | CF Montréal | 36 | 8 |
| 33 | Matteo Mancosu
CF Montréal | CF Montréal | 20 | 7 |
| - | Juan Agudelo
New England Revolution | New England Revolution | 24 | 7 |
| - | Michael de Leeuw
Chicago Fire FC | Chicago Fire FC | 18 | 7 |
| - | Tesho Akindele
FC Dallas | FC Dallas | 33 | 7 |
| - | Kei Kamara
New England Revolution | New England Revolution | 21 | 7 |
| - | Mike Grella
New York Red Bulls | New York Red Bulls | 34 | 7 |
| - | Kevin Doyle
Colorado Rapids | Colorado Rapids | 30 | 7 |
| - | Juan Martínez
Real Salt Lake | Real Salt Lake | 33 | 7 |
| - | C.J. Sapong
Philadelphia Union | Philadelphia Union | 32 | 7 |
| - | Benny Feilhaber
Sporting Kansas City | Sporting Kansas City | 31 | 7 |
| 43 | Julio Baptista
Orlando City SC | Orlando City SC | 23 | 6 |
| - | Álvaro Saborío
D.C. United | D.C. United | 19 | 6 |
| - | Mauro Manotas
Houston Dynamo FC | Houston Dynamo FC | 22 | 6 |
| - | Jacob Peterson
Sporting Kansas City | Sporting Kansas City | 22 | 6 |
| - | Mike Magee
LA Galaxy | LA Galaxy | 33 | 6 |
| - | Gyasi Zardes
LA Galaxy | LA Galaxy | 19 | 6 |
| - | Dominique Badji
Colorado Rapids | Colorado Rapids | 31 | 6 |
| - | Andrew Wenger
Houston Dynamo FC | Houston Dynamo FC | 32 | 6 |